Asthma and COPD overlap pathophysiology of ACO

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Burden of asthma and COPD overlap (ACO) in Taiwan: a nationwide population-based study

BACKGROUND Patients with symptoms of both asthma and chronic obstructive pulmonary disease (COPD) may be classified with the term asthma-COPD overlap (ACO). ACO is of considerable interest as it is currently poorly characterised and has been associated with worse health outcomes and higher healthcare costs compared with COPD or asthma alone. Patients with ACO in Asia remain poorly described, an...

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The Asthma-COPD Overlap Syndrome.

Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.

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The Asthma-COPD Overlap Syndrome

Asthma and Chronic Obstructive Pulmonary Disease (COPD) are pulmonary disorders characterized by various degrees of airflow limitation, inflammation and tissue remodeling. Bronchial asthma, an allergic disease that develops in childhood, is physiologically characterized by reversible airflow obstruction. It has an episodic course and a generally favorable prognosis, as it responds well to anti-...

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Asthma-COPD overlap syndrome and precision medicine.

Differentiation of asthma and chronic obstructive pulmonary disease (COPD) in symptomatic patients has been extremely difficult clinically in many instances. This situation led to the formulation of the so-called “Dutch hypothesis” in 1961,1 cited by Christenson.2 The theory postulates that obstructive lung disease occur in a continuum, with asthma and COPD being expressions of the same disease...

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Heterogeneity of asthma–COPD overlap syndrome

Many patients suffering from asthma or COPD have overlapping features of both diseases. However, a phenotypical approach for evaluating asthma-COPD overlap syndrome (ACOS) has not been established. In this report, we examined the phenotypes in patients with ACOS. Patients diagnosed with ACOS between 2011 and 2015 were identified and classified into four phenotype groups. Group A was composed of...

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ژورنال

عنوان ژورنال: Allergology International

سال: 2018

ISSN: 1323-8930

DOI: 10.1016/j.alit.2018.01.001